Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13295541 | 0.83 | GAA (0.61) | GAAL3MBTL1MAPK8MAPK9MAPK10 | |
| SCHEMBL10093022 | 0.78 | GAA (0.41) | GAARAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL14572952 | 0.77 | GAA (0.44) | GAAL3MBTL1 | |
| SCHEMBL1852640 | 0.77 | GAA (0.39) | GAAL3MBTL1 | |
| SCHEMBL3605937 | 0.73 | RAB9A (0.37) | GAARAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL9218943 | 0.72 | RAB9A (0.45) | RAB9ANPC1LMNASMN1; SMN2MAPT | |
| SCHEMBL12844013 | 0.71 | ALDH1A1 (0.40) | GAARAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL23384509 | 0.69 | SMN1; SMN2 (0.48) | GAARAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL5274911 | 0.68 | GABRB3 (0.36) | RAB9ANPC1LMNAALDH1A1NR1I2 | |
| SCHEMBL14981439 | 0.68 | PDE5A (0.38) | GAARAB9ANPC1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| EP-2589294-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | ACHE, TUBA3C, NAAA | GAA 1508/4885RAB9A 1739/4885NPC1 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.