Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1470307 | 0.98 | HRH3 (0.57) | HRH3PYCR1MAPT | |
| SCHEMBL8252162 | 0.83 | HRH3 (0.63) | HRH3PYCR1MAPT | |
| SCHEMBL13778397 | 0.82 | HRH3 (0.61) | HRH3PYCR1MAPT | |
| Chloromethane SCHEMBL27279686 | 0.80 | HRH3 (0.53) | HRH3 | |
| SCHEMBL3180482 | 0.80 | CNR2 (0.56) | HRH3 | |
| SCHEMBL9286253 | 0.79 | HRH3 (0.57) | HRH3 | |
| SCHEMBL31260447 | 0.78 | HRH3 (0.57) | HRH3PYCR1MAPT | |
| Hydrochloric Acid SCHEMBL11571118 | 0.78 | HRH3 (0.55) | HRH3 | |
| SCHEMBL22340500 | 0.77 | HRH3 (0.55) | HRH3PYCR1 | |
| SCHEMBL10990959 | 0.77 | MAPT (0.58) | HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094706-B1 | SUBSTITUTED 2,5-DFFLYDRO-3H-PYRAZOLO[4,3-C]PYRIDAZIN-3-ONE DERIVATIVES, PREPARATION THEREOF AND USE OF SAME AS CANNABINOID CB1 RECEPTOR LIGANDS | SANOFI AVENTIS (FR) | 2011-01-05 | — | — | EP | disclosed |
| EP-2094706-A2 | SUBSTITUTED 2,5-DFFLYDRO-3H-PYRAZOLO[4,3-C]PYRIDAZIN-3-ONE DERIVATIVES, PREPARATION THEREOF AND USE OF SAME AS CANNABINOID CB1 RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008068424-A2 | SUBSTITUTED 2,5-DIHYDRO-3H-PYRAZOLO[4,3-C]PYRIDAZIN-3-ONE DERIVATIVES, PREPARATION THEREOF AND USE OF SAME AS CANNABINOID CB1 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2008-06-12 | — | — | WO | disclosed |