Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17589604 | 0.85 | SETD7 (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL875920 | 0.71 | DRD2 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17589454 | 0.62 | GAA (0.36) | ALDH1A1KMT2ASRD5A1 | |
| SCHEMBL10094758 | 0.62 | GAA (0.36) | ALDH1A1KMT2ASRD5A1 | |
| SCHEMBL17589455 | 0.62 | GAA (0.36) | ALDH1A1KMT2ASRD5A1 | |
| SCHEMBL435022 | 0.62 | METAP1 (0.44) | MEN1KMT2ASRD5A1 | |
| SCHEMBL435023 | 0.62 | DDB1 (0.48) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL8312132 | 0.62 | GAA (0.38) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL11576098 | 0.62 | KDM4E (0.45) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL5986558 | 0.60 | HSD17B10 (0.44) | ALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468751-B1 | Processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole | MEDICHEM SA (ES) | 2016-03-16 | — | — | EP | disclosed |
| EP-2468751-A2 | Processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole | Medichem, S.A. (ES) | 2012-06-27 | — | — | EP | disclosed |