Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875920 | 0.86 | DRD2 (0.44) | SETD7HRH4DRD2DRD4CHRM2 | |
| SCHEMBL10094757 | 0.85 | ALDH1A1 (0.31) | KMT2AALDH1A1MAPTMEN1LMNA | |
| SCHEMBL3152103 | 0.81 | DRD2 (0.44) | SETD7HRH4DRD2DRD4CHRM2 | |
| SCHEMBL11364230 | 0.73 | SETD7 (0.53) | SETD7HRH4DRD2DRD4CHRM2 | |
| SCHEMBL17975306 | 0.71 | NR1H2 (0.51) | HRH4ELANENR1H2NR1H3MAPT | |
| SCHEMBL11653199 | 0.70 | ELANE (0.39) | SETD7HRH4ELANECYP19A1KMT2A | |
| SCHEMBL9475303 | 0.70 | ELANE (0.62) | HRH4ELANENPC1PKMRAB9A | |
| SCHEMBL19885347 | 0.69 | ELANE (0.45) | SETD7HRH4ELANECYP19A1DRD2 | |
| SCHEMBL19685845 | 0.69 | NPC1 (0.39) | SETD7HRH4ELANENPC1PKM | |
| SCHEMBL14771691 | 0.69 | SETD7 (0.33) | SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468751-B1 | Processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole | MEDICHEM SA (ES) | 2016-03-16 | — | — | EP | disclosed |