SCHEMBL1009785

SCHEMBL1009785

CSCCCCCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18902512 1.00 LMNA (0.45)
SCHEMBL2515557 1.00 LMNA (0.45)
SCHEMBL7487393 1.00 LMNA (0.45)
SCHEMBL4602333 1.00
SCHEMBL283183 0.97
SCHEMBL101773 0.87
Hydrochloric Acid SCHEMBL18130992 0.84
SCHEMBL7155535 0.83 TRPA1 (0.50)
SCHEMBL7156742 0.83 TRPA1 (0.50)
SCHEMBL7155007 0.83 TRPA1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037424-B1 NOVEL QUINOLINE-SUBSTITUTED COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2017-11-08 EP disclosed
US-20150210701-A1 TREATMENT OF HELICOBACTER PYLORI INFECTIONS ALBERTEINSTIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2015-07-30 US disclosed
WO-2014025842-A1 TREATMENT OF HELICOBACTER PYLORI INFECTIONS ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2014-02-13 WO disclosed
US-20110028746-A1 METHOD FOR THE DECARBOXYLATIVE HYDROFORMYLATION OF ALPHA, BETA- UNSATURATED CARBOXYLIC ACIDS BASF SE (DE) 2011-02-03 US disclosed
EP-2268397-A1 METHOD FOR THE DECARBOXYLATIVE HYDROFORMYLATION OF , ALPHA, BETA -UNSATURATED CARBOXYLIC ACIDS BASF SE (DE) 2011-01-05 EP disclosed
WO-2009118341-A1 METHOD FOR THE DECARBOXYLATIVE HYDROFORMYLATION OF α,β-UNSATURATED CARBOXYLIC ACIDS BASF SE (DE) 2009-10-01 WO disclosed
EP-1460071-B1 N-HETEROARYLNICOTINAMIDE DERIVATIVES MITSUI CHEMICALS AGRO INC (JP) 2009-09-16 EP disclosed
US-7399775-B2 β-amyloid protein production/secretion inhibitor DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2008-07-15 US disclosed
US-20080039816-A1 Carbohydrate-Encapsulated Quantum Dots for Bilogical Imaging The Government of the United States of America as represented by the Secretary, Department of (US) 2008-02-14 US disclosed
US-20070293495-A1 BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-12-20 US disclosed
EP-1466898-A1 BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-10-13 EP disclosed
EP-1460071-A1 N-HETEROARYLNICOTINAMIDE DERIVATIVES Sankyo Agro Company, Limited (JP) 2004-09-22 EP disclosed
US-6525000-B1 N-aminoureas are reacted with formaldehyde to give methyleneimino ureas, cyclizing these to give tetrahydro-4H-1,3,4-oxa(or thia)diazines, and cyclizing the fused triazoles using phosgene; herbicides BASF AKTIENGESELLSCHAFT (DE) 2003-02-25 US disclosed
EP-1095045-B1 METHOD FOR PRODUCING ANELLATED TRIAZOLES AND NEW ANELLATED TRIAZOLES AND THEIR USE BASF AG (DE) 2003-01-15 EP disclosed
EP-0835248-B1 1-AMINO-3-BENZYLURACILS BASF AG (DE) 2001-02-21 EP disclosed
EP-0835248-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1998-04-15 EP disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
WO-1997001543-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed