SCHEMBL10099482

SCHEMBL10099482

CCCCO[C@@H]1[C@@H]2OC(C)(C)O[C@H]2O[C@@H]1[C@@H](O)CO

nearest known ligand 0.78

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.78
CYP1A2 P05177 1/20 0.78
THPO P40225 1/20 0.78
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
ALDH1A1 P00352 3/20 0.40
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
ATM Q13315 1/20 0.37
GLB1 P16278 1/20 0.33
CYP2C9 P11712 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
HIF1A Q16665 1/20 0.31
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9008124 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL14853690 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL12429068 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL14817692 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL13496252 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL10182543 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL13865179 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL15588473 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL16298765 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1
SCHEMBL14536569 1.00 LMNA (0.78) LMNACYP1A2THPOKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2809678-B1 AN EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORP (US) 2017-03-22 EP disclosed
US-8987430-B2 Efficient and scalable process for the manufacture of fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2015-03-24 US disclosed
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-10-03 US disclosed
US-8420790-B2 Efficient and scalable process for the manufacture of Fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-16 US disclosed
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LMNA 1630/4885CYP1A2 913/4885THPO 99/4885
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 LMNA 1630/4885CYP1A2 913/4885THPO 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.