Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ESRRA | P11474 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23036593 | 0.81 | TDP1 (0.42) | ALDH1A1ALOX15CYP2C9HSD17B10NPSR1 | |
| SCHEMBL5735681 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL30490014 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ESRRAALOX15NR1I2LMNA | |
| SCHEMBL7204289 | 0.76 | ESRRA (0.72) | ALDH1A1ESRRAALOX15NR1I2LMNA | |
| SCHEMBL35535 | 0.74 | ALDH1A1 (0.73) | ALDH1A1ESRRAALOX15NR1I2LMNA | |
| SCHEMBL29362042 | 0.74 | ALDH1A1 (0.73) | ALDH1A1ESRRAALOX15NR1I2LMNA | |
| SCHEMBL6142004 | 0.74 | ALDH1A1 (0.73) | ALDH1A1ESRRAALOX15NR1I2LMNA | |
| SCHEMBL9008266 | 0.74 | ESRRA (0.59) | ALDH1A1ESRRAALOX15NR1I2LMNA | |
| SCHEMBL5737701 | 0.73 | CA12 (0.40) | ALDH1A1HSD17B10GAANR1H4ATM | |
| SCHEMBL5737146 | 0.73 | GAA (0.32) | ALDH1A1GAAATMXBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207365-B2 | Polymeric salen compounds and methods thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| US-20090030172-A1 | POLYMERIC SALEN COMPOUNDS AND METHODS THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030172-A1 | POLYMERIC SALEN COMPOUNDS AND METHODS THEREOF | F12, CHRM1, H1-0 | ALDH1A1 1087/4885ESRRA 1852/4885ALOX15 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.