Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212749 | 0.90 | MAPT (0.45) | RAB9AMAPTPOLBPKMAPP | |
| SCHEMBL8739445 | 0.85 | SMN1; SMN2 (0.47) | RAB9AMAPTPOLBAPPSMN1; SMN2 | |
| SCHEMBL8738077 | 0.81 | PPIB (0.45) | RAB9AMAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL16142224 | 0.78 | APP (0.41) | RAB9AMAPTAPPCYP2C19KMT2A | |
| SCHEMBL16601930 | 0.76 | RAB9A (0.39) | RAB9AMAPTPOLBPKMCYP2C19 | |
| SCHEMBL18033968 | 0.76 | MAPT (0.48) | RAB9AMAPTPOLBPKMAPP | |
| SCHEMBL28326337 | 0.74 | MAPT (0.47) | RAB9AMAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1485830 | 0.74 | POLB (0.59) | RAB9AMAPTPOLBPKMAPP | |
| SCHEMBL13232496 | 0.74 | MAPT (0.61) | RAB9AMAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL4824629 | 0.73 | SMN1; SMN2 (0.54) | RAB9AMAPTPOLBAPPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9717694-B2 | Peptide/particle delivery systems | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-01 | — | — | US | disclosed |
| US-20120114759-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114759-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | RAB9A 561/4885MAPT 975/4885POLB 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.