Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738077 | 0.86 | PPIB (0.45) | RAB9ANPC1MAPTALDH1A1HTT | |
| SCHEMBL8739445 | 0.82 | SMN1; SMN2 (0.47) | RAB9AMAPTALDH1A1HTTLMNA | |
| SCHEMBL16140052 | 0.81 | LMNA (0.41) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL8739105 | 0.81 | LMNA (0.41) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL17069545 | 0.81 | LMNA (0.35) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL4824465 | 0.78 | TOP2A (0.49) | RAB9ANPC1MAPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL4829831 | 0.76 | TOP2A (0.48) | RAB9ANPC1MAPTALDH1A1HTT | |
| SCHEMBL10100136 | 0.76 | RAB9A (0.42) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL4824629 | 0.73 | SMN1; SMN2 (0.54) | RAB9AMAPTALDH1A1HTTLMNA | |
| SCHEMBL16601936 | 0.73 | TDP1 (0.34) | RAB9ALMNACYP1A2DRD3SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |