SCHEMBL10100825

SCHEMBL10100825

Cc1cc2c(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)ccc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c2cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HDAC4 P56524 1/20 0.38
GPR3 P46089 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HDAC6 Q9UBN7 2/20 0.35
RORC P51449 1/20 0.35
POLB P06746 2/20 0.34
NQO2 P16083 1/20 0.34
PLA2G2A P14555 1/20 0.34
PTPN1 P18031 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10100822 0.90 KDM4E (0.53) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL23989286 0.88 KDM4E (0.52) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL18566858 0.88 KDM4E (0.44) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL10100830 0.88 L3MBTL1 (0.64) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL4401754 0.87 KDM4E (0.47) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL4404634 0.87 KDM4E (0.50) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL2758577 0.86 KDM4E (0.53) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL12438134 0.86 KDM4E (0.46) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL14416349 0.86 L3MBTL1 (0.61) KDM4EATML3MBTL1HDAC4GPR3
SCHEMBL14416364 0.86 L3MBTL1 (0.61) KDM4EATML3MBTL1HDAC4GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed