SCHEMBL10100822

SCHEMBL10100822

Cc1cc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)c(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ATM Q13315 1/20 0.53
HDAC4 P56524 1/20 0.40
GPR3 P46089 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.37
FTO Q9C0B1 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PGR P06401 1/20 0.37
POLB P06746 2/20 0.36
AKR1C4 P17516 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
NQO2 P16083 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
PTPN1 P18031 2/20 0.35
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2758577 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL10100825 0.90 KDM4E (0.50) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL4404634 0.86 KDM4E (0.50) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL15752310 0.86 KDM4E (0.53) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL12438134 0.85 KDM4E (0.46) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL14429702 0.85 L3MBTL1 (0.63) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL21943769 0.85 L3MBTL1 (0.63) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL14416325 0.85 L3MBTL1 (0.57) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL14429664 0.85 L3MBTL1 (0.63) KDM4EL3MBTL1ATMHDAC4GPR3
SCHEMBL13382377 0.84 L3MBTL1 (0.44) KDM4EL3MBTL1ATMHDAC4GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10340460-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-02 US disclosed
US-20190103564-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-04-04 US disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10340460-B2 Organic electroluminescent element EML4, LAGE3, ELOC KDM4E 746/4885L3MBTL1 278/4885ATM 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.