SCHEMBL10100860

SCHEMBL10100860

CCC(CC)(c1ccc(-n2c3ccccc3c3ccccc32)cc1)c1ccc(C(CC)(CC)c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ESR1 P03372 4/20 0.42
ESR2 Q92731 3/20 0.42
MAPK8 P45983 1/20 0.41
PTPN1 P18031 2/20 0.38
GPR3 P46089 1/20 0.38
PGR P06401 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
KIF11 P52732 1/20 0.37
PPARG P37231 1/20 0.36
POLB P06746 1/20 0.36
HDAC6 Q9UBN7 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129252 0.84 KDM4E (0.52) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL15444629 0.83 KDM4E (0.50) KDM4EATML3MBTL1MAPK8PTPN1
SCHEMBL13179728 0.82 KDM4E (0.53) KDM4EATML3MBTL1MAPK8PTPN1
SCHEMBL16358449 0.81 KDM4E (0.53) KDM4EATML3MBTL1MAPK8PTPN1
SCHEMBL15304576 0.81 KDM4E (0.48) KDM4EATML3MBTL1MAPK8PTPN1
SCHEMBL13616260 0.81 RORA (0.41) KDM4EATML3MBTL1PGRCYP1A2
SCHEMBL29875801 0.79 KDM4E (0.59) KDM4EATML3MBTL1MAPK8PTPN1
SCHEMBL10039116 0.79 KDM4E (0.59) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL10100856 0.79 KDM4E (0.59) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL674884 0.79 KDM4E (0.59) KDM4EATML3MBTL1MAPK8PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed