SCHEMBL674884

SCHEMBL674884

CC(C)(C)c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
ATM Q13315 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PPARG P37231 4/20 0.47
PMM2 O15305 1/20 0.46
MPI P34949 1/20 0.46
PHOSPHO1 Q8TCT1 1/20 0.46
PPARA Q07869 2/20 0.46
GPR3 P46089 1/20 0.41
DNM1 Q05193 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KIF11 P52732 3/20 0.40
POLB P06746 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
TSHR P16473 1/20 0.38
PTPN1 P18031 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875801 1.00 KDM4E (0.59) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL24703436 0.98 KDM4E (0.57) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL19735294 0.94 KDM4E (0.53) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL24703411 0.94 KDM4E (0.64) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL19342624 0.94 KDM4E (0.53) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL45712 0.93 KDM4E (0.52) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL15745992 0.93 KDM4E (0.52) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL15745996 0.91 KDM4E (0.50) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL15447689 0.91 KDM4E (0.60) KDM4EATML3MBTL1PPARGPMM2
SCHEMBL13714521 0.91 L3MBTL1 (0.53) KDM4EATML3MBTL1PPARGPMM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461717-B Thermal activation delayed fluorescence material based on 1,10 ferrosins and preparation method thereof, application 华南理工大学 2018-01-05 CN claimed
CN-103992305-B 1,8-naphthalimide derivative compound organic electroluminescent main material and device 四川大学 2017-05-17 CN claimed
CN-105461717-A Thermal activation delayed fluorescence material based on 1,10-phenanthroline and preparing method and application thereof UNIV SOUTH CHINA TECH 2016-04-06 CN claimed
CN-102827203-A Phosphorescent host material and preparation method and application thereof DONGGUAN CAIXIAN ORGANIC LIGHT EMITTING TECHNOLOGY CO LTD 2012-12-19 CN claimed
US-12043627-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-07-23 US disclosed
US-12043627-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-07-23 US disclosed
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-11917900-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11917900-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-20070262704-A1 Carbazole-based Compounds and Their Application Wong, Ken-Tsung (TW) 2007-11-15 US disclosed
US-20070262704-A1 Carbazole-based Compounds and Their Application Wong, Ken-Tsung (TW) 2007-11-15 US disclosed
US-20070167614-A1 Organic opto-electronic polymer and use thereof ETERNAL CHEMICAL CO., LTD. 2007-07-19 US disclosed
US-20070167614-A1 Organic opto-electronic polymer and use thereof ETERNAL CHEMICAL CO., LTD. 2007-07-19 US disclosed
US-20060149022-A1 Polymeric (organic) light emitting diodes, (PLED, OLED); polyarylenevinylene polymer containing N-substituted carbazole units, and another aromatic ring unit; blends with organometallic fluorescent or phosphorescent molecule such as phenylpyridine iridium complex MERCK PATENT GMBH (DE) 2006-07-06 US disclosed
CN-1747981-A Carbazole-containing conjugated polymers and blends, their preparation and use COVION ORGANIC SEMICONDUCTORS (DE) 2006-03-15 CN disclosed
EP-1592729-A2 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF Covion Organic Semiconductors GmbH (DE) 2005-11-09 EP disclosed
WO-2004070772-A2 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167614-A1 Organic opto-electronic polymer and use thereof PPOX, CYBA, OGFOD1 KDM4E 4026/4885ATM 2199/4885L3MBTL1 3192/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND KDM4E 3586/4885ATM 4463/4885L3MBTL1 440/4885
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, NR2E3 KDM4E 1039/4885ATM 2081/4885L3MBTL1 622/4885
US-20070262704-A1 Carbazole-based Compounds and Their Application CCNI, CYP3A5, CCNC KDM4E 1107/4885ATM 1948/4885L3MBTL1 3380/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KDM4E 3179/4885ATM 4355/4885L3MBTL1 822/4885
US-11917900-B2 Organic electroluminescent materials and devices OTC, OSBP, OCIAD2 KDM4E 3522/4885ATM 4067/4885L3MBTL1 1605/4885
US-12043627-B2 Compound and color conversion film comprising same CRY1, FLI1, FDFT1 KDM4E 662/4885ATM 3455/4885L3MBTL1 2708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.