Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5991543 | 0.86 | IRAK4 (0.41) | IRAK4PDCD1LG2CD274IRAK1 | |
| SCHEMBL14285588 | 0.86 | IRAK4 (0.41) | IRAK4PDCD1LG2CD274IRAK1 | |
| SCHEMBL14309089 | 0.79 | IRAK4 (0.40) | IRAK4PDCD1LG2CD274IRAK1 | |
| SCHEMBL4378121 | 0.79 | IRAK4 (0.35) | IRAK4PDCD1LG2CD274 | |
| SCHEMBL28284360 | 0.76 | IRAK4 (0.35) | IRAK4PDCD1LG2CD274 | |
| SCHEMBL5991452 | 0.76 | IRAK4 (0.35) | IRAK4PDCD1LG2CD274 | |
| SCHEMBL22354600 | 0.75 | IRAK4 (0.42) | IRAK4PDCD1LG2CD274 | |
| SCHEMBL5994524 | 0.75 | IRAK4 (0.42) | IRAK4PDCD1LG2CD274 | |
| SCHEMBL5992949 | 0.75 | IRAK4 (0.37) | IRAK4PDCD1LG2CD274 | |
| SCHEMBL12409742 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041194-A1 | NITROGEN AND SULFUR-CONTAINING HETROCYCLE DERIVATIVES | TRIAD MULTITECH PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-20110269953-A1 | Nitrogen and Sulfur-Containing Heterocycle Derivatives | ARMILLI MURTY N | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041194-A1 | NITROGEN AND SULFUR-CONTAINING HETROCYCLE DERIVATIVES | HRH4, HNMT, TST | IRAK4 3423/4885PDCD1LG2 4299/4885CD274 2563/4885 |
| US-20110269953-A1 | Nitrogen and Sulfur-Containing Heterocycle Derivatives | TST, HNMT, HRH4 | IRAK4 2929/4885PDCD1LG2 4430/4885CD274 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.