SCHEMBL10101832

SCHEMBL10101832

CNc1cc(NC)c(/N=N/c2c(C#N)cnn2-c2ncccn2)c(NC)n1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10101841 0.90 NPC1 (0.30) NPC1RAB9A
SCHEMBL13068734 0.84 CDK2 (0.32) NPC1RAB9A
SCHEMBL10101949 0.79 NPC1 (0.32) NPC1RAB9A
SCHEMBL10101831 0.79
SCHEMBL10106457 0.78 SMN1; SMN2 (0.33) NPC1RAB9A
SCHEMBL10101825 0.77 TSHR (0.33)
SCHEMBL10101956 0.77 ALOX15 (0.36) NPC1RAB9A
SCHEMBL10101932 0.77 ALDH1A1 (0.32) NPC1RAB9A
SCHEMBL10101903 0.77
SCHEMBL10102040 0.77 CSNK2A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed