⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10101867 | 0.83 | LMNA (0.30) | — | |
| SCHEMBL660988 | 0.83 | GAA (0.38) | — | |
| SCHEMBL2589156 | 0.74 | LMNA (0.34) | — | |
| SCHEMBL10101848 | 0.72 | ACHE (0.43) | — | |
| SCHEMBL11734726 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL10101893 | 0.71 | HMGCR (0.41) | — | |
| SCHEMBL10101864 | 0.69 | IRAK4 (0.38) | — | |
| SCHEMBL13475557 | 0.69 | LMNA (0.37) | — | |
| SCHEMBL6055422 | 0.68 | LMNA (0.44) | — | |
| SCHEMBL13356070 | 0.68 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | THE UNIVERSITY OF MELBOURNE of ROYAL PARADE PARKVILLE (AU) | 2012-02-23 | — | — | US | disclosed |