SCHEMBL10101983

SCHEMBL10101983

CNc1nc(N2CCSCC2)c(C#N)c(C)c1/N=N/c1c(C#N)cnn1-c1ncccn1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10101897 0.92 ALDH1A1 (0.35) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL10101964 0.92 KDM4E (0.37) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL10101969 0.91 ALDH1A1 (0.36) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL10101978 0.90 SMN1; SMN2 (0.36) KDM4EALDH1A1HPGDTSHR
SCHEMBL10101952 0.90 ALDH1A1 (0.38) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL10101967 0.90 ALDH1A1 (0.34) KDM4EALDH1A1HPGD
SCHEMBL10101984 0.89 CSNK2A1 (0.36) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL10101999 0.87 KDM4E (0.36) KDM4EALDH1A1HPGD
SCHEMBL10101913 0.86 ALDH1A1 (0.35) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL10101966 0.84 KDM4E (0.34) KDM4EALDH1A1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed