SCHEMBL10101984

SCHEMBL10101984

Cc1c(C#N)c(N2CCSCC2)nc(Nc2ccccc2)c1/N=N/c1c(C#N)cnn1-c1ncccn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 6/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TRPV1 Q8NER1 2/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
HIF1A Q16665 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CTSK P43235 1/20 0.31
PTPN11 Q06124 1/20 0.31
PIK3CD O00329 1/20 0.31
CDK4 P11802 1/20 0.30
CCND3 P30281 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10101983 0.89 KDM4E (0.38) ALDH1A1KDM4EHPGDTSHRHSD17B10
SCHEMBL10101964 0.88 KDM4E (0.37) ALDH1A1KDM4EHPGDTSHRHSD17B10
SCHEMBL10102105 0.82 ALDH1A1 (0.38) CSNK2A1ALDH1A1MEN1KMT2ACDK4
SCHEMBL10102041 0.82 ALDH1A1 (0.38) CSNK2A1ALDH1A1MEN1KMT2ACDK4
SCHEMBL10101897 0.81 ALDH1A1 (0.35) CSNK2A1ALDH1A1KDM4EHPGDTSHR
SCHEMBL10101969 0.81 ALDH1A1 (0.36) ALDH1A1KDM4EHPGDTSHRHSD17B10
SCHEMBL10101978 0.80 SMN1; SMN2 (0.36) ALDH1A1KDM4EHPGDTSHRMEN1
SCHEMBL10101952 0.79 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDTSHRHSD17B10
SCHEMBL10101967 0.79 ALDH1A1 (0.34) ALDH1A1KDM4EHPGDHIF1ASMN1; SMN2
SCHEMBL10101913 0.77 ALDH1A1 (0.35) CSNK2A1ALDH1A1KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed