SCHEMBL10101988

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5482884	0.90	EGFR (1.00)	EGFRLCKRAF1FBP1KDR
	Hydrochloric Acid SCHEMBL5475745	0.89	EGFR (1.00)	EGFRLCKRAF1FBP1KDR
	SCHEMBL13604745	0.88	EGFR (0.82)	EGFRLCKRAF1BRAFKDR
	SCHEMBL2100551	0.87	EGFR (0.82)	EGFRLCKRAF1BRAFFBP1
	SCHEMBL6674055	0.87	KDR (0.82)	EGFRLCKRAF1BRAFFBP1
	SCHEMBL22367405	0.86	EGFR (0.82)	EGFRFBP1KDRRETKIF5B
	SCHEMBL15052584	0.86	BRAF (1.00)	RAF1BRAF
	SCHEMBL14964757	0.84	EGFR (0.81)	EGFRLCKRAF1BRAFKDR
	SCHEMBL5239599	0.84	EGFR (0.80)	EGFRLCKRAF1BRAFKDR
	SCHEMBL13285584	0.83	EGFR (0.83)	EGFRLCKRAF1BRAFFBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.