SCHEMBL10102024

SCHEMBL10102024

CNc1nc(Nc2cccc(C)c2)c(C#N)c(C)c1/N=N/c1c(C#N)cnn1-c1ncccn1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
LMNA P02545 2/20 0.37
RXFP1 Q9HBX9 1/20 0.37
TP53 P04637 1/20 0.34
FER P16591 4/20 0.34
SYK P43405 1/20 0.34
EGFR P00533 4/20 0.33
KDM4E B2RXH2 3/20 0.32
AURKA O14965 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10102065 0.93 KMT2A (0.30) KMT2A
SCHEMBL10102041 0.91 ALDH1A1 (0.38) KMT2ARXFP1MEN1ALDH1A1
SCHEMBL10102105 0.91 ALDH1A1 (0.38) KMT2ARXFP1MEN1ALDH1A1
SCHEMBL10102001 0.91 CSNK2A1 (0.35) KMT2ALMNARXFP1EGFRKDM4E
SCHEMBL10102018 0.89 ALDH1A1 (0.31) NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL10101976 0.87 CDK4 (0.35) KMT2ALMNATP53KDM4EMEN1
SCHEMBL10102051 0.86 TNF (0.37) EGFRKDM4ENPC1ALDH1A1RAB9A
SCHEMBL10106460 0.86 KDM4E (0.35) KDM4EALDH1A1GAAMAPT
SCHEMBL10101989 0.86 HPGD (0.44) LMNATP53KDM4ENPC1ALDH1A1
SCHEMBL10101974 0.86 KDM4E (0.41) KMT2ARXFP1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
EP-2253674-A1 AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, AND INKJET RECORDING INK FUJIFILM Corporation (JP) 2010-11-24 EP disclosed