SCHEMBL1010218

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1634511	0.96	PPARA (0.60)	PPARAPPARGALOX5SLC22A12CYSLTR2
	SCHEMBL1634988	0.95	PPARA (0.62)	PPARAPPARGALOX5SLC22A12CYSLTR2
	SCHEMBL1634208	0.93	PPARA (0.54)	PPARAPPARGSLC22A12CYSLTR2CYSLTR1
	SCHEMBL954242	0.86	FFAR1 (0.54)	PPARAPPARGSLC22A12CYSLTR2CYSLTR1
	SCHEMBL1010327	0.85	SLC22A12 (0.50)	PPARAPPARGSLC22A12MAPK1L3MBTL1
	SCHEMBL959881	0.82	CYSLTR2 (0.58)	PPARAPPARGSLC22A12CYSLTR2CYSLTR1
	SCHEMBL3902689	0.82	PPARA (0.60)	PPARAPPARGALOX5CYSLTR2CYSLTR1
	SCHEMBL1856638	0.82	PPARA (0.59)	PPARAPPARGALOX5
	SCHEMBL4568940	0.82	SLC22A12 (0.57)	PPARAPPARGSLC22A12CYP2D6CYP4F2
	SCHEMBL1634802	0.81	CYSLTR2 (0.57)	PPARAPPARGSLC22A12CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.