Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 2/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15960729 | 0.89 | PDGFRB (0.47) | ALDH1A1POLBLMNAL3MBTL1MAPT | |
| SCHEMBL13168044 | 0.88 | PKM (0.50) | ALDH1A1POLBSMN1; SMN2LMNACCR6 | |
| SCHEMBL15826940 | 0.86 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2LMNACCR6 | |
| SCHEMBL15826934 | 0.86 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2LMNACCR6 | |
| SCHEMBL27249063 | 0.83 | ALDH1A1 (0.51) | ALDH1A1POLBSMN1; SMN2LMNACCR6 | |
| SCHEMBL10102461 | 0.82 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAL3MBTL1KMT2A | |
| SCHEMBL300188 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBSMN1; SMN2LMNACCR6 | |
| SCHEMBL27474529 | 0.81 | ALDH1A1 (0.57) | ALDH1A1POLBSMN1; SMN2LMNACCR6 | |
| SCHEMBL27474538 | 0.80 | ALDH1A1 (0.53) | ALDH1A1POLBSMN1; SMN2LMNACCR6 | |
| SCHEMBL1012650 | 0.80 | ALDH1A1 (0.53) | ALDH1A1POLBSMN1; SMN2LMNACCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43098-E1 | Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-10 | — | — | US | disclosed |