Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | KIF5B | P33176 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475406 | 0.87 | EHMT2 (0.64) | RETKIF5BTLR9TLR7EHMT2 | |
| SCHEMBL10102456 | 0.87 | EGFR (0.49) | RETKIF5BALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2921178 | 0.85 | EHMT2 (0.65) | RETKIF5BTLR9TLR7EHMT2 | |
| SCHEMBL11953085 | 0.85 | EGFR (0.48) | ALDH1A1KDM4EL3MBTL1TSHRHTT | |
| SCHEMBL14444641 | 0.80 | RET (0.53) | RETKIF5BEHMT2EHMT1SRC | |
| SCHEMBL20347544 | 0.80 | EHMT2 (0.47) | ALDH1A1KDM4EL3MBTL1TSHRHTT | |
| SCHEMBL16707263 | 0.79 | EHMT2 (0.56) | ALDH1A1KDM4EL3MBTL1TSHRHTT | |
| SCHEMBL16707264 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1TSHRHTT | |
| SCHEMBL13355147 | 0.77 | EHMT2 (0.64) | RETKIF5BTLR9TLR7EHMT2 | |
| SCHEMBL11953082 | 0.77 | SRC (0.49) | RETKIF5BSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43098-E1 | Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-10 | — | — | US | disclosed |