Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.64 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.62 |
| ▸ | KIT | P10721 | 4/20 | 0.61 |
| ▸ | RET | P07949 | 3/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | KIF5B | P33176 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 4/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.58 |
| ▸ | FLT1 | P17948 | 2/20 | 0.58 |
| ▸ | FLT4 | P35916 | 2/20 | 0.58 |
| ▸ | AXL | P30530 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.58 |
| ▸ | MERTK | Q12866 | 2/20 | 0.58 |
| ▸ | PLK4 | O00444 | 1/20 | 0.58 |
| ▸ | GAK | O14976 | 1/20 | 0.58 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299046 | 0.88 | AURKA (0.67) | KITRETABCB11KIF5BKDR | |
| SCHEMBL2475406 | 0.88 | EHMT2 (0.64) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL4431962 | 0.87 | EHMT2 (0.69) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL2924110 | 0.87 | ENPP1 (0.64) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL4430442 | 0.87 | EHMT2 (0.69) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL2921178 | 0.87 | EHMT2 (0.65) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL3955512 | 0.86 | ENPP1 (0.65) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL2921945 | 0.86 | ENPP1 (0.65) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL4426202 | 0.86 | EHMT2 (0.70) | EHMT2EHMT1TLR9TLR7KIT | |
| SCHEMBL10088086 | 0.85 | ACHE (0.58) | EHMT2KITRETKIF5BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709640-B2 | Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-05-04 | — | — | US | disclosed |