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SCHEMBL10102829

SCHEMBL10102829

C=CC(=O)Oc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 2/20 0.46
▸ ALDH1A1 P00352 1/20 0.43
▸ PDE6D O43924 1/20 0.43
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ PPARG P37231 1/20 0.40
▸ PPARA Q07869 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ MAPT P10636 3/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ CYP2C19 P33261 2/20 0.38
▸ GAA P10253 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ PTGES O14684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9915724 1.00 THRB (0.46) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL9915700 0.97 ALDH1A1 (0.46) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL172431 0.97 ALDH1A1 (0.46) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL9915728 0.97 ALDH1A1 (0.46) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL12149085 0.97 ALDH1A1 (0.46) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL9915752 0.96 THRB (0.43) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL12149075 0.94 THRB (0.50) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL13051080 0.94 THRB (0.50) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL12149033 0.94 THRB (0.50) THRBALDH1A1PDE6DMEN1KMT2A
SCHEMBL11938791 0.94 THRB (0.50) THRBALDH1A1PDE6DMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3177963-B1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH CO LTD (JP) 2020-02-19 — — EP disclosed
US-8148038-B2 Image bearing member, process cartridge, image forming apparatus and method of forming image bearing member RICOH COMPANY, LTD. (JP) 2012-04-03 — — US disclosed
US-8148038-B2 Image bearing member, process cartridge, image forming apparatus and method of forming image bearing member RICOH COMPANY, LTD. (JP) 2012-04-03 — — US disclosed
US-7718335-B2 Image bearing member, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2010-05-18 — — US disclosed
US-7718335-B2 Image bearing member, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2010-05-18 — — US disclosed
US-20090148180-A1 IMAGE BEARING MEMBER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS AND METHOD OF FORMING IMAGE BEARING MEMBER RICOH COMPANY, LTD. (JP) 2009-06-11 — — US disclosed
US-20090148180-A1 IMAGE BEARING MEMBER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS AND METHOD OF FORMING IMAGE BEARING MEMBER RICOH COMPANY, LTD. (JP) 2009-06-11 — — US disclosed
US-20070196750-A1 IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LIMITED. (JP) 2007-08-23 — — US disclosed
US-20070196750-A1 IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LIMITED. (JP) 2007-08-23 — — US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 — — US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 — — US disclosed