SCHEMBL1010436

SCHEMBL1010436

CCCCNC(=O)N(C(=O)OC)c1nc2ccccc2[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
BCHE P06276 1/20 0.47
TRPC3 Q13507 1/20 0.47
TRPC4 Q9UBN4 1/20 0.47
TRPC5 Q9UL62 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
LMNA P02545 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
SPHK2 Q9NRA0 1/20 0.44
SPHK1 Q9NYA1 1/20 0.44
DRD2 P14416 1/20 0.44
DRD3 P35462 1/20 0.44
POLB P06746 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL10792070 0.92 ALDH1A1 (0.41) ALDH1A1NPC1RAB9ABCHETRPC3
SCHEMBL3706435 0.88 ALDH1A1 (0.49) ALDH1A1NPC1RAB9ABCHETRPC3
SCHEMBL3670861 0.85 POLB (0.45) ALDH1A1SMN1; SMN2LMNACYP2D6CYP2C19
Dimethirimol SCHEMBL11794538 0.85 ALDH1A1 (0.38) ALDH1A1NPC1RAB9ABCHETRPC3
SCHEMBL11305337 0.82 SMN1; SMN2 (0.45) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL3715154 0.79 ALDH1A1 (0.47) ALDH1A1NPC1RAB9ABCHETRPC3
SCHEMBL11198128 0.78 POLB (0.46) ALDH1A1NPC1RAB9ABCHETRPC3
SCHEMBL9241589 0.76 ALDH1A1 (0.49) ALDH1A1NPC1RAB9ABCHETRPC3
SCHEMBL4888617 0.75 LMNA (0.56) ALDH1A1NPC1RAB9ABCHESMN1; SMN2
SCHEMBL10576084 0.75 ALDH1A1 (0.47) ALDH1A1NPC1RAB9ABCHETRPC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030149088-A1 HIV treatment UNIVERSITY OF ARIZONA FOUNDATION (US) 2003-08-07 US claimed
WO-2002041891-A2 HIV TREATMENT WITH BENZIMIDAZOLES THE PROCTER & GAMBLE COMPANY (US) 2002-05-30 WO claimed
EP-0817564-B1 MEDIUM FOR STORING, TRANSPORTING AND/OR GROWING A PLANT RANPAK CORP (US) 2000-10-11 EP claimed
US-5767138-A ADMINISTERING TO MAMMAL 2-CARBAMYL-BENZIMIDAZOLE DERIVATIVE FUNGICIDE WITH SIDE EFFECT REDUCTION PROCTER & GAMBLE COMPANY (US) 1998-06-16 US claimed
EP-0831816-A1 USE OF BENZIMIDAZOLES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF LEUKEMIA THE PROCTER & GAMBLE COMPANY (US) 1998-04-01 EP claimed
EP-0821586-A1 A PHARMACEUTICAL COMPOSITION CONTAINING BENZIMIDAZOLE FOR INHIBITING THE GROWTH OF CANCERS THE PROCTER & GAMBLE COMPANY (US) 1998-02-04 EP claimed
EP-0817564-A1 MEDIUM FOR STORING, TRANSPORTING AND/OR GROWING A PLANT RANPAK CORPORATION (US) 1998-01-14 EP claimed
WO-1996040122-A1 USE OF BENZIMIDAZOLES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF LEUKEMIA THE PROCTER & GAMBLE COMPANY (US) 1996-12-19 WO claimed
WO-1996032107-A1 A PHARMACEUTICAL COMPOSITION CONTAINING BENZIMIDAZOLE FOR INHIBITING THE GROWTH OF CANCERS THE PROCTER & GAMBLE COMPANY (US) 1996-10-17 WO claimed
WO-1996028013-A1 MEDIUM FOR STORING, TRANSPORTING AND/OR GROWING A PLANT RANPAK CORP. (US) 1996-09-19 WO claimed
EP-0147222-A2 Composition for use in preserving hydrocarbon products STERWIN AG. (CH) 1985-07-03 EP claimed
EP-0093604-A1 Fungicidal carbamates and thiolcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-09 EP claimed
JP-6298615-A None JP disclosed
WO-2023218403-A1 COMPOSITION COMPRISING A PHTHALIMIDE FUNGICIDE AND AN ACETIC ACID-BASED BUFFER ADAMA MAKHTESHIM LTD. (IL) 2023-11-16 WO disclosed
EP-4255187-A1 DITHIOCARBAMATE FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2023-10-11 EP disclosed
US-11466246-B2 Microbial conversion of CO2 and other C1 substrates to vegan nutrients, fertilizers, biostimulants, and systems for accelerated soil carbon sequestration KIVERDI, INC. (US) 2022-10-11 US disclosed
US-3935224-A 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932509-A FUNGICIDES, VIRICIDES CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149088-A1 HIV treatment BCOR, CYP3A4, NNT ALDH1A1 1790/4885NPC1 23/4885RAB9A 4112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.