Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 11/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | KDM4A | O75164 | 2/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 4/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104042 | 0.94 | MEN1 (0.68) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10104048 | 0.92 | RAB9A (0.47) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10313112 | 0.90 | MEN1 (0.62) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10104170 | 0.87 | MEN1 (0.65) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL12657328 | 0.87 | MEN1 (0.59) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10104286 | 0.87 | MEN1 (0.59) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10104174 | 0.86 | MEN1 (0.64) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10104097 | 0.86 | MEN1 (0.60) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL12657238 | 0.85 | MEN1 (0.69) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10104280 | 0.84 | RAB9A (0.41) | RAB9AMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8562693-B2 | Method of dyeing and lightening keratin materials in the presence of a reducing agent comprising a fluorescent deisulphide dye | L'OREAL (FR) | 2013-10-22 | — | — | US | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | KRT18, DSG1, ALPG | RAB9A 4038/4885MEN1 3833/4885KMT2A 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.