Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 17/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904021 | 0.89 | ADORA2B (0.60) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL10104730 | 0.82 | ADORA2B (0.60) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL9903991 | 0.76 | ADORA2A (0.72) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL9904033 | 0.75 | ADORA2B (0.75) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL8183967 | 0.72 | ADORA1 (0.55) | ADORA2AADORA2BADORA1 | |
| SCHEMBL10104740 | 0.71 | MAOB (0.57) | — | |
| SCHEMBL9904195 | 0.71 | ADORA2B (0.73) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL9904089 | 0.69 | ADORA2B (0.55) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL3949936 | 0.68 | ADORA2B (0.59) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL1944369 | 0.67 | ADORA2B (1.00) | ADORA2AADORA2BADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465859-A1 | 8-Triazolylxanthine derivatives, processes for their production and their use as adenosine receptor antagonists | Life & Brain GmbH (DE) | 2012-06-20 | — | — | EP | disclosed |