Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904085 | 0.87 | MAOB (0.59) | MAOBMAOALMNAGAASMN1; SMN2 | |
| SCHEMBL17786245 | 0.73 | SMN1; SMN2 (0.71) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL17786270 | 0.72 | LMNA (0.64) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL10104773 | 0.71 | ADORA2A (0.51) | — | |
| SCHEMBL30185437 | 0.71 | CYP19A1 (0.72) | SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL29275463 | 0.71 | CYP19A1 (0.72) | SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL14623976 | 0.70 | LMNA (0.84) | ALDH1A1LMNAGAASMN1; SMN2TSHR | |
| SCHEMBL13939659 | 0.69 | ALDH1A1 (0.80) | MAOBALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL16029691 | 0.69 | LMNA (0.63) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL10104730 | 0.69 | ADORA2B (0.60) | ALDH1A1TSHRMAPK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465859-A1 | 8-Triazolylxanthine derivatives, processes for their production and their use as adenosine receptor antagonists | Life & Brain GmbH (DE) | 2012-06-20 | — | — | EP | disclosed |