Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14188259 | 0.85 | MEN1 (0.33) | ALDH1A1TSHRCHRM2CHRM5CHRM3 | |
| SCHEMBL9999667 | 0.84 | MEN1 (0.33) | ALDH1A1TSHRCHRM2CHRM5CHRM3 | |
| SCHEMBL12672151 | 0.81 | LMNA (0.41) | LMNATAAR1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL1060074 | 0.80 | TAAR1 (0.55) | LMNATAAR1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL36896 | 0.80 | LMNA (0.54) | LMNATAAR1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21899454 | 0.77 | LMNA (0.51) | LMNATAAR1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL5608205 | 0.77 | LMNA (0.51) | LMNATAAR1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21000360 | 0.74 | MGLL (0.30) | — | |
| SCHEMBL1549904 | 0.73 | MEN1 (0.37) | LMNATAAR1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL20029979 | 0.73 | LMNA (0.45) | LMNATAAR1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1834976-B1 | Anion-binding polymers and uses thereof | ILYPSA INC (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1834976-A1 | Anion-binding polymers and uses thereof | Ilypsa, Inc. (US) | 2007-09-19 | — | — | EP | disclosed |