Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163657 | 1.00 | TK2 (0.53) | TK2KDM4EALDH1A1PYGM | |
| SCHEMBL10101281 | 1.00 | TK2 (0.53) | TK2KDM4EALDH1A1PYGM | |
| SCHEMBL27093309 | 0.95 | TK2 (0.48) | TK2PYGM | |
| SCHEMBL27093412 | 0.93 | TK2 (0.49) | TK2PYGM | |
| SCHEMBL27094653 | 0.93 | TK2 (0.48) | TK2KDM4EALDH1A1 | |
| SCHEMBL27093456 | 0.91 | TK2 (0.51) | TK2PYGM | |
| SCHEMBL27094652 | 0.91 | TK2 (0.46) | TK2PYGM | |
| SCHEMBL19834971 | 0.90 | TK2 (0.48) | TK2PYGM | |
| SCHEMBL27093256 | 0.90 | TK2 (0.50) | TK2PYGM | |
| SCHEMBL19834965 | 0.88 | TK2 (0.45) | TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101385-B2 | Materials and methods for the generation of transcripts comprising modified nucleotides | ARCHEMIX CORP. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100120024-A1 | Materials and methods for the generation of transcripts comprising modified nucleotides | ARCHEMIX CORP. | 2010-05-13 | — | — | US | disclosed |
| WO-2008078180-A2 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | ARCHEMIX CORP. (US) | 2008-07-03 | — | — | WO | disclosed |