SCHEMBL19834971

SCHEMBL19834971

CO[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1n1cc(C(=O)NCc2ccc3ccccc3c2)c(=O)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TK2 O00142 11/20 0.48
▸ P2RY2 P41231 1/20 0.43
▸ PYGM P11217 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19834970 0.92 TK2 (0.47) TK2P2RY2PYGM
SCHEMBL19834969 0.92 TK2 (0.45) TK2P2RY2PYGM
SCHEMBL10101281 0.90 TK2 (0.53) TK2PYGM
SCHEMBL29163657 0.90 TK2 (0.53) TK2PYGM
SCHEMBL10104844 0.90 TK2 (0.53) TK2PYGM
SCHEMBL27093412 0.89 TK2 (0.49) TK2PYGM
SCHEMBL27093309 0.89 TK2 (0.48) TK2P2RY2PYGM
SCHEMBL27094653 0.88 TK2 (0.48) TK2P2RY2
SCHEMBL19834965 0.87 TK2 (0.45) TK2
SCHEMBL27094652 0.87 TK2 (0.46) TK2P2RY2PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961860-A Aptamers that bind to IL-6 and their use in treating or diagnosing IL-6 mediated disorders 私募蛋白质体公司 2021-06-15 — — CN claimed
EP-3044334-B1 PDGF AND VEGF APTAMERS HAVING IMPROVED STABILITY AND THEIR USE IN TREATING PDGF AND VEGF MEDIATED DISEASES AND DISORDERS SOMALOGIC INC (US) 2020-08-12 — — EP claimed
CN-110643610-A Nucleic acid compounds for binding complement component 3 proteins 私募蛋白质体公司 2020-01-03 — — CN claimed
EP-3224361-B1 NUCLEIC ACID COMPOUNDS FOR BINDING GROWTH DIFFERENTIATION FACTOR 11 SOMALOGIC INC (US) 2019-06-19 — — EP claimed
EP-3149173-B1 NUCLEIC ACID COMPOUNDS FOR BINDING TO COMPLEMENT COMPONENT 3 PROTEIN SOMALOGIC INC (US) 2018-02-07 — — EP claimed
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SOMALOGIC OPERATING CO., INC. (US) 2024-07-04 — — US disclosed
CN-109439664-B Aptamer binding to IL-6 and use thereof in the treatment or diagnosis of IL-6 mediated disorders 私募蛋白质体操作有限公司 2024-03-08 — — CN disclosed
EP-4323374-A1 MODIFIED NUCLEOSIDES SomaLogic Operating Co., Inc. (US) 2024-02-21 — — EP disclosed
CN-112961860-A Aptamers that bind to IL-6 and their use in treating or diagnosing IL-6 mediated disorders 私募蛋白质体公司 2021-06-15 — — CN disclosed
CN-106459979-B Nucleic acid compounds for binding complement component 3 proteins 私募蛋白质体公司 2020-07-21 — — CN disclosed
CN-110643610-A Nucleic acid compounds for binding complement component 3 proteins 私募蛋白质体公司 2020-01-03 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SARS1, RNGTT, PABPC1 TK2 3270/4885P2RY2 4661/4885PYGM 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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