SCHEMBL27094652

SCHEMBL27094652

CO[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1n1cc(C(=O)NCc2ccc(F)cc2)c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TK2 O00142 10/20 0.46
▸ P2RY2 P41231 1/20 0.42
▸ PYGM P11217 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27093287 0.92 TK2 (0.44) TK2P2RY2PYGM
SCHEMBL10104844 0.91 TK2 (0.53) TK2PYGM
SCHEMBL10101281 0.91 TK2 (0.53) TK2PYGM
SCHEMBL29163657 0.91 TK2 (0.53) TK2PYGM
SCHEMBL27093309 0.90 TK2 (0.48) TK2P2RY2PYGM
SCHEMBL27093412 0.88 TK2 (0.49) TK2PYGM
SCHEMBL19834971 0.87 TK2 (0.48) TK2P2RY2PYGM
SCHEMBL27093335 0.85 PKM (0.46) TK2
SCHEMBL27094653 0.84 TK2 (0.48) TK2P2RY2
SCHEMBL19834965 0.83 TK2 (0.45) TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SOMALOGIC OPERATING CO., INC. (US) 2024-07-04 — — US disclosed
EP-4323374-A1 MODIFIED NUCLEOSIDES SomaLogic Operating Co., Inc. (US) 2024-02-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SARS1, RNGTT, PABPC1 TK2 3270/4885P2RY2 4661/4885PYGM 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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