Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466729 | 0.97 | HIF1A (0.41) | HIF1ATDP1SNCAESR1TAAR1 | |
| Bromide SCHEMBL8986440 | 0.95 | HIF1A (0.36) | HIF1ATDP1SNCAESR1TAAR1 | |
| Iodide SCHEMBL723719 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| SCHEMBL7865522 | 0.94 | HIF1A (0.39) | HIF1ATDP1SNCAESR1TAAR1 | |
| Water SCHEMBL4816145 | 0.94 | HIF1A (0.39) | HIF1ATDP1SNCAESR1TAAR1 | |
| Fluoride Ion SCHEMBL7874729 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL7874744 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Iodide SCHEMBL3352425 | 0.92 | HIF1A (0.38) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Fluoride SCHEMBL10615440 | 0.92 | HIF1A (0.38) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Fluoride Ion SCHEMBL10604942 | 0.92 | HIF1A (0.38) | HIF1ATDP1ESR1TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456064-B | Synthetic method of caronic anhydride and its derivative | 上海璨谊生物科技有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-113087888-B | Indoor mixed high-speed cured polyester resin and preparation method and application thereof | 浙江光华科技股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114456064-A | Synthesis method of caronic anhydride and derivatives thereof | 上海璨谊生物科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-108690005-B | Synthesis method of nitro-containing natural product chrysamides B and diastereoisomer-compound thereof | 兰州大学 | 2021-08-24 | — | — | CN | claimed |
| CN-109553758-A | A kind of high definition transfer specialty polyesters and preparation method thereof | 安徽恒明工程技术有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-109503820-A | A kind of fast low temperature cure type polyester resin and preparation method thereof | 安徽恒明工程技术有限公司 | 2019-03-22 | — | — | CN | claimed |
| US-6248161-B1 | Preparation of permanent color inks from water-soluble colorants using specific phosphonium salts | HEWLETT-PACKARD COMPANY | 2001-06-19 | — | — | US | claimed |
| US-4603213-A | Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-07-29 | — | — | US | claimed |
| EP-4739652-A1 | LIPIDS AND COMPOSITIONS THEREOF | Kernal Biologics, Inc. (US) | 2026-05-13 | — | — | EP | disclosed |
| US-20260116845-A1 | LIPIDS AND COMPOSITIONS THEREOF | KERNAL BIOLOGICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| CN-120843086-A | Sb3+Near infrared luminescent material of activated zinc-based zero-dimensional organic-inorganic hybrid metal halide and preparation method thereof | 北京工商大学 | 2025-10-28 | — | — | CN | disclosed |
| WO-2025010290-A1 | LIPIDS AND COMPOSITIONS THEREOF | KERNAL BIOLOGICS, INC. (US) | 2025-01-09 | — | — | WO | disclosed |
| CN-114456064-B | Synthetic method of caronic anhydride and its derivative | 上海璨谊生物科技有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-113087888-B | Indoor mixed high-speed cured polyester resin and preparation method and application thereof | 浙江光华科技股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-5275950-A | Process for the preparation of a renin inhibiting compound | ABBOTT LABORATORIES (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0526575-A1 | EPOXY RESIN SYSTEMS MODIFIED WITH LOW VISCOSITY STATISTICAL MONOFUNCTIONAL REACTIVE POLYMERS | THE B.F. GOODRICH COMPANY (US) | 1993-02-10 | — | — | EP | disclosed |
| WO-1991017213-A1 | EPOXY RESIN SYSTEMS MODIFIED WITH LOW VISCOSITY STATISTICAL MONOFUNCTIONAL REACTIVE POLYMERS | THE B.F. GOODRICH COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |
| US-4603213-A | Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0172347-A2 | Renin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4351767-A | FROM DITOSYLOXYS-CHOLEST-24-ENE OXIDE, WITTIG REACTION | KAISER EMIL T | 1982-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116845-A1 | LIPIDS AND COMPOSITIONS THEREOF | LIPC, LIPA, NPC1L1 | ACHE 4733/4885HIF1A 3518/4885TDP1 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.