Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466729 | 0.97 | HIF1A (0.41) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| SCHEMBL7865522 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Bromide SCHEMBL1010505 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Iodide SCHEMBL723719 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Water SCHEMBL4816145 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Fluoride Ion SCHEMBL7874729 | 0.94 | HIF1A (0.39) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Fluoride SCHEMBL10615440 | 0.92 | HIF1A (0.38) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Iodide SCHEMBL3352425 | 0.92 | HIF1A (0.38) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Fluoride Ion SCHEMBL10604942 | 0.92 | HIF1A (0.38) | HIF1ATDP1ESR1TAAR1SLC6A2 | |
| Bromide SCHEMBL8986440 | 0.89 | HIF1A (0.36) | HIF1ATDP1ESR1TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316575-B1 | MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | claimed |
| US-20210206727-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | UNIV OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2021-07-08 | — | — | US | disclosed |
| US-10766866-B2 | Deterrents for arthropods and marine organisms | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2020-09-08 | — | — | US | disclosed |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | 2019-09-26 | — | — | US | disclosed |
| EP-0834496-B1 | Preparation of diaryl carbonate | UBE INDUSTRIES (JP) | 2001-08-16 | — | — | EP | disclosed |
| EP-0834495-B1 | Process for preparing diaryl carbonate | UBE INDUSTRIES (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5892091-A | PHOSPHOROUS CATALYSTS AND HALOGEN ATOMS | UBE INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| US-5892089-A | FROM DIARYL OXALATE IN LIQUID PHASE BY DECARBONYLATION USING ORGANIC PHOSHORUS COMPOUND CATALYST | UBE INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0737665-B1 | Process for preparation of diaryl carbonate | UBE INDUSTRIES (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5792883-A | Preparation of diaryl carbonate | UBE INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0834496-A1 | Preparation of diaryl carbonate | UBE INDUSTRIES, LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |
| EP-0834495-A1 | Process for preparing diaryl carbonate | UBE INDUSTRIES, LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |
| EP-0826658-A1 | Catalyst for decarbonylation reaction | UBE INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5648510-A | DECARBONYLATION OF OXALATE | UBE INDUSTRIES, LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0737665-A1 | Process for preparation of diaryl carbonate | UBE INDUSTRIES, LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766866-B2 | Deterrents for arthropods and marine organisms | ALG1, NISCH, ALG8 | SLC6A2 583/4885SLC6A3 377/4885ACHE 8/4885 |
| US-20210206727-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | ALG1, ALG8, DDT | SLC6A2 421/4885SLC6A3 225/4885ACHE 8/4885 |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | ALG1, NISCH, ALG8 | SLC6A2 583/4885SLC6A3 377/4885ACHE 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.