Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31280241 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11TDP1FFAR1CPT2 | |
| SCHEMBL31279936 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11TDP1FFAR1CPT2 | |
| SCHEMBL1009937 | 0.84 | FFAR1 (0.34) | CYP4F2CYP4A11TDP1FFAR1CPT2 | |
| SCHEMBL18987409 | 0.83 | MEN1 (0.40) | TDP1FFAR1GPR84FFAR4PPARA | |
| SCHEMBL31280022 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11TDP1FFAR1CPT2 | |
| SCHEMBL1012264 | 0.80 | MAPT (0.42) | TDP1FFAR1CPT2ACLYACACB | |
| SCHEMBL28133882 | 0.80 | CYP4F2 (0.41) | CYP4F2CYP4A11TDP1FFAR1CPT2 | |
| SCHEMBL1010556 | 0.77 | KDM4E (0.46) | TDP1FFAR1CPT2ACLYFNTA | |
| SCHEMBL8654541 | 0.77 | MEN1 (0.37) | HTT | |
| SCHEMBL4581998 | 0.77 | MEN1 (0.37) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268319-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | Universität Ulm (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009109798-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | UNIVERSITÄT ULM (DE) | 2009-09-11 | — | — | WO | disclosed |