Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010541 | 0.80 | CYP4F2 (0.47) | ACLYFFAR1CPT2TDP1ACACB | |
| SCHEMBL18850771 | 0.79 | MAPT (0.39) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9256362 | 0.79 | CYP2D6 (0.43) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1009937 | 0.78 | FFAR1 (0.34) | ACLYFFAR1CPT2TDP1ACACB | |
| SCHEMBL18987409 | 0.78 | MEN1 (0.40) | MAPTHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL20021228 | 0.77 | MAPT (0.44) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9216534 | 0.74 | CYP4F2 (0.37) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL602186 | 0.73 | ARG1 (0.53) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL600737 | 0.73 | ARG1 (0.53) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL600736 | 0.73 | ARG1 (0.53) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268319-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | Universität Ulm (DE) | 2011-01-05 | — | — | EP | disclosed |