SCHEMBL4581998

SCHEMBL4581998

C1COCCOCCOCCO1.CCCCCCCCCCCCC(C)(C(=O)O)C(=O)OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CNR2 P34972 1/20 0.36
GGPS1 O95749 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HTT P42858 1/20 0.35
EPHX1 P07099 2/20 0.34
HPGD P15428 1/20 0.34
RECQL P46063 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8654541 1.00 MEN1 (0.37) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL599715 1.00 MEN1 (0.37) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL18987409 0.89 MEN1 (0.40) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL9442790 0.87 GGPS1 (0.41) MEN1KMT2AGGPS1HTTHSD17B10
SCHEMBL5905927 0.83 MEN1 (0.38) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL487136 0.82 MAPT (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL11362555 0.81 EPHX1 (0.37) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL29690472 0.80 MEN1 (0.40) MEN1MAPTKMT2AATML3MBTL1
Potassium SCHEMBL29455954 0.79 MAPT (0.44) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL1010541 0.77 CYP4F2 (0.47) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040180391-A1 Sliver type autonomous biosensors CASE WESTERN RESERVE UNIVERSITY 2004-09-16 US claimed
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-02-24 US disclosed
US-11026952-B2 Small molecules for mouse satellite cell proliferation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-06-08 US disclosed
US-20200352957-A1 SMALL MOLECULE SCREENING FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2020-11-12 US disclosed
US-10660902-B2 Method of increasing satellite cell proliferation with an HDAC inhibitor PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-05-26 US disclosed
EP-3411040-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION President and Fellows of Harvard College (US) 2018-12-12 EP disclosed
US-20180153902-A1 SMALL MOLECULE SCREENING FOR MOUSE SATELLITE CELL PROLIFERATION HOWARD HUGHES MEDICAL INSTITUTE 2018-06-07 US disclosed
WO-2017136480-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-10 WO disclosed
WO-2012174537-A2 SMALL MOLECULE SCREENING FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-12-20 WO disclosed
US-7373195-B2 Ion sensor for long term use in complex medium MEDTRONIC, INC. (US) 2008-05-13 US disclosed
US-20060025748-A1 Ion sensor for long term use in complex medium MEDTRONIC, INC. 2006-02-02 US disclosed
US-20040122475-A1 Electrochemical neuron systems MYRICK ANDREW J (US) 2004-06-24 US disclosed
WO-2002020087-A1 ELECTROCHEMICAL NEURON SYSTEMS MYRICK ANDREW J (US) 2002-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11026952-B2 Small molecules for mouse satellite cell proliferation MKI67, MYLK2, MYH2 MEN1 4412/4885MAPT 4150/4885KMT2A 1908/4885
US-10660902-B2 Method of increasing satellite cell proliferation with an HDAC inhibitor HDAC4, HDAC1, HDAC5 MEN1 4576/4885MAPT 3910/4885KMT2A 86/4885
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 MEN1 4412/4885MAPT 4150/4885KMT2A 1908/4885
US-20180153902-A1 SMALL MOLECULE SCREENING FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 MEN1 4381/4885MAPT 4009/4885KMT2A 1776/4885
US-20200352957-A1 SMALL MOLECULE SCREENING FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 MEN1 4381/4885MAPT 4009/4885KMT2A 1776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.