Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10105298 | 0.85 | KMT2A (0.51) | KMT2ARAD52RXFP1MEN1ABCB1 | |
| SCHEMBL12955612 | 0.79 | SLC2A1 (0.41) | KMT2ARAD52RXFP1MEN1ABCB1 | |
| SCHEMBL1105731 | 0.77 | KMT2A (0.55) | KMT2ARAD52RXFP1MEN1HTR2C | |
| SCHEMBL11223239 | 0.76 | KMT2A (0.59) | KMT2ARAD52RXFP1MEN1HTR2C | |
| SCHEMBL8622919 | 0.76 | ALDH1A1 (0.43) | KMT2ARAD52RXFP1ABCB1GAA | |
| SCHEMBL2742045 | 0.73 | KMT2A (0.52) | KMT2ARAD52RXFP1MEN1HTR2C | |
| SCHEMBL10411260 | 0.72 | KMT2A (0.55) | KMT2ARAD52RXFP1MEN1HTR2C | |
| SCHEMBL20115140 | 0.72 | KMT2A (0.55) | KMT2ARAD52RXFP1MEN1HTR2C | |
| SCHEMBL2269084 | 0.72 | KMT2A (0.60) | KMT2ARAD52RXFP1MEN1HTR2C | |
| SCHEMBL13503134 | 0.72 | KMT2A (0.55) | KMT2ARAD52RXFP1MEN1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010494-B1 | SPECIFIC MONOCATIONIC MONOCHROMOPHORIC COMPOUNDS OF HYDRAZONE TYPE COMPRISING A 2-, 4-PYRIDINIUM OR 2-, 4-QUINOLINIUM UNIT, SYNTHESIS THEREOF, DYE COMPOSITIONS CONTAINING THEM, AND METHOD FOR DYEING KERATIN FIBRES | OREAL (FR) | 2012-02-01 | — | — | EP | disclosed |