Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 7/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621175 | 0.82 | MAPT (0.43) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL8618393 | 0.81 | DHODH (0.44) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL10105429 | 0.76 | KMT2A (0.50) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL13592780 | 0.75 | KMT2A (0.53) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL8618775 | 0.75 | MAPT (0.54) | ALDH1A1HSD17B10KDM4EMAPTTSHR | |
| SCHEMBL14366798 | 0.75 | KMT2A (0.53) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL14366800 | 0.75 | RAD52 (0.39) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL8621124 | 0.74 | AHR (0.51) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL8615949 | 0.74 | TERT (0.40) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL11223239 | 0.73 | KMT2A (0.59) | ALDH1A1HSD17B10KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659582-B1 | Reversible thermochromic composition | PILOT INK CO LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5558700-A | QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR | THE PILOT INK CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0659582-A1 | Reversible thermochromic composition | THE PILOT INK CO., LTD. (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-4446321-A | COLOR FORMERS, CARBON-FREE DUPLICATION | STERLING DRUG INC. (US) | 1984-05-01 | — | — | US | disclosed |
| US-4363503-A | FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS | STERLING DRUG INC. (US) | 1982-12-14 | — | — | US | disclosed |