Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453685 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMEN1MAPT | |
| SCHEMBL30464716 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMEN1MAPT | |
| SCHEMBL434992 | 0.75 | ALDH1A1 (0.62) | ALDH1A1GAAHPGDMEN1MAPT | |
| SCHEMBL13817764 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAAHPGDMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7405088 | 0.75 | MAPT (0.57) | ALDH1A1GAAHPGDMEN1MAPT | |
| Hydrochloric Acid SCHEMBL12500827 | 0.75 | MAPT (0.57) | ALDH1A1GAAHPGDMEN1MAPT | |
| SCHEMBL14745262 | 0.73 | ALDH1A1 (0.55) | ALDH1A1GAAHPGDMEN1MAPT | |
| SCHEMBL17888445 | 0.73 | ALDH1A1 (0.51) | ALDH1A1GAAHPGDMEN1MAPT | |
| SCHEMBL25044261 | 0.73 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMEN1MAPT | |
| SCHEMBL2616322 | 0.73 | MEN1 (0.58) | ALDH1A1GAAHPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010494-B1 | SPECIFIC MONOCATIONIC MONOCHROMOPHORIC COMPOUNDS OF HYDRAZONE TYPE COMPRISING A 2-, 4-PYRIDINIUM OR 2-, 4-QUINOLINIUM UNIT, SYNTHESIS THEREOF, DYE COMPOSITIONS CONTAINING THEM, AND METHOD FOR DYEING KERATIN FIBRES | OREAL (FR) | 2012-02-01 | — | — | EP | disclosed |