SCHEMBL434992

SCHEMBL434992

Cc1ccc2c(c1)CCCN2C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
GAA P10253 2/20 0.62
MAPT P10636 1/20 0.62
HPGD P15428 1/20 0.62
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
NOTUM Q6P988 1/20 0.50
CHRM2 P08172 1/20 0.50
CHRM4 P08173 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
TSHR P16473 3/20 0.48
HTT P42858 1/20 0.48
PDK1 Q15118 1/20 0.48
PDK2 Q15119 1/20 0.48
PDK3 Q15120 1/20 0.48
PDK4 Q16654 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14256038 0.94 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL2616784 0.88 NOTUM (0.58) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL2616323 0.86 ALDH1A1 (0.60) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL23729376 0.81 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL3178012 0.81 MEN1 (0.58) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL12101222 0.81 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL2616322 0.81 MEN1 (0.58) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL7262642 0.81 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL25044261 0.81 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL20427833 0.81 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400505-A1 PEPTIDE-UREA DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF Bivision Pharmaceuticals, Inc (CN) 2024-07-17 EP disclosed
US-11820932-B2 Polymerisable liquid crystal material and polymerised liquid crystal film MERCK PATENT GMBH (DE) 2023-11-21 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-11706938-B2 Photoelectric conversion element and photoelectric conversion module RICOH COMPANY, LTD. (JP) 2023-07-18 US disclosed
US-11706938-B2 Photoelectric conversion element and photoelectric conversion module RICOH COMPANY, LTD. (JP) 2023-07-18 US disclosed
US-20230183239-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF ABBVIE INC (US) 2023-06-15 US disclosed
US-20230183239-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF ABBVIE INC (US) 2023-06-15 US disclosed
EP-3632443-B1 ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2023-06-07 EP disclosed
US-20230171975-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTRIC CONVERSION MODULE, ELECTRONIC DEVICE, AND PARTITION RICOH COMPANY, LTD., (JP) 2023-06-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
EP-1787979-A1 SULFONAMIDE DERIVATIVE SELECTIVELY INHIBITING MMP-13 Shionogi Co., Ltd. (JP) 2007-05-23 EP disclosed
US-7220522-B2 Electrophotographic photoreceptor, method for manufacturing the electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2007-05-22 US disclosed
US-7220522-B2 Electrophotographic photoreceptor, method for manufacturing the electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2007-05-22 US disclosed
US-20070105838-A1 Bicyclic Benzamide Compoundssa as Histamine H3 Receptor Ligand Useful in the Treatment of Neurological Diseases GLAXO GROUP LIMITED (GB) 2007-05-10 US disclosed
US-20070105838-A1 Bicyclic Benzamide Compoundssa as Histamine H3 Receptor Ligand Useful in the Treatment of Neurological Diseases GLAXO GROUP LIMITED (GB) 2007-05-10 US disclosed
EP-0174717-B1 BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS FISONS plc (GB) 1992-01-22 EP disclosed
EP-0174717-A1 Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors FISONS plc (GB) 1986-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105838-A1 Bicyclic Benzamide Compoundssa as Histamine H3 Receptor Ligand Useful in the Treatment of Neurological Diseases HRH3, HRH4, HRH1 ALDH1A1 2111/4885MEN1 2996/4885KMT2A 155/4885
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 IKZF1, IKZF3, IKZF2 ALDH1A1 4344/4885MEN1 3335/4885KMT2A 869/4885
US-20230183239-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF ENPP1, ENPP3, STING1 ALDH1A1 1769/4885MEN1 3315/4885KMT2A 3342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.