SCHEMBL10105952

SCHEMBL10105952

Cc1c(O)c(C(=O)Nc2ccccc2Cl)cc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.57
▸ POLB P06746 3/20 0.57
▸ CASP3 P42574 1/20 0.57
▸ ATM Q13315 1/20 0.57
▸ SENP8 Q96LD8 1/20 0.57
▸ SENP7 Q9BQF6 1/20 0.57
▸ SENP6 Q9GZR1 1/20 0.57
▸ CYP1A2 P05177 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ AR P10275 1/20 0.52
▸ CBR1 P16152 1/20 0.52
▸ AKR1C3 P42330 1/20 0.52
▸ F12 P00748 1/20 0.51
▸ RAB9A P51151 5/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ LMNA P02545 2/20 0.47
▸ MAOB P27338 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13497402 0.90 TRPV1 (0.48) NPC1POLBCASP3ATMSENP8
SCHEMBL13373967 0.82 PTGS1 (0.56) NPC1POLBRAB9AKMT2AMEN1
SCHEMBL11662821 0.82 NPC1 (0.52) NPC1POLBCASP3ATMSENP8
SCHEMBL12149320 0.82 NPC1 (0.52) NPC1POLBCASP3ATMSENP8
SCHEMBL14422306 0.81 CYP1A2 (0.56) NPC1POLBCASP3ATMSENP8
SCHEMBL5575194 0.81 NPC1 (0.51) NPC1POLBCASP3ATMSENP8
SCHEMBL5575201 0.81 AR (0.55) NPC1POLBCASP3ATMSENP8
SCHEMBL1087471 0.81 MEN1 (0.57) NPC1POLBCASP3SENP7SENP6
SCHEMBL14463132 0.81 MAOA (0.58) NPC1POLBF12RAB9AKMT2A
SCHEMBL11776026 0.80 MAPT (0.49) NPC1POLBCASP3ATMSENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8974998-B2 Method of image forming with a photoreceptor and toner MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-10 — — US disclosed
US-8974998-B2 Method of image forming with a photoreceptor and toner MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-10 — — US disclosed
US-8871413-B2 Toners for electrostatic-image development, cartridge employing toner for electrostatic-image development, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-28 — — US disclosed
US-8871413-B2 Toners for electrostatic-image development, cartridge employing toner for electrostatic-image development, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-28 — — US disclosed
US-8741530-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-06-03 — — US disclosed
US-8741530-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-06-03 — — US disclosed
US-20130309604-A1 IMAGE-FORMING APPARATUS AND CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-11-21 — — US disclosed
US-20130143156-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-06-06 — — US disclosed
US-20130143156-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-06-06 — — US disclosed
US-8404411-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-26 — — US disclosed
US-20090180807-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-07-16 — — US disclosed
US-20090180807-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-07-16 — — US disclosed
US-20090136861-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-05-28 — — US disclosed
US-20090136861-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-05-28 — — US disclosed
US-20090053634-A1 Image Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-26 — — US disclosed
US-20090053634-A1 Image Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-26 — — US disclosed
US-20090041500-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-12 — — US disclosed
US-20090041500-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-12 — — US disclosed
US-7245851-B2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-17 — — US disclosed
US-7245851-B2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-17 — — US disclosed
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