Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662821 | 0.90 | NPC1 (0.52) | MAPTTRPV1POLBNPC1CASP3 | |
| SCHEMBL11598294 | 0.89 | PPARG (0.45) | MAPTPOLBNPC1CASP3ATM | |
| SCHEMBL11624948 | 0.85 | ALDH1A1 (0.51) | MAPTPOLBNPC1KMT2AMEN1 | |
| SCHEMBL11770628 | 0.85 | NPC1 (0.53) | MAPTPOLBNPC1KMT2AMEN1 | |
| SCHEMBL11561031 | 0.82 | MAPT (0.52) | MAPTPOLBNPC1KMT2AMEN1 | |
| SCHEMBL11664267 | 0.82 | RAB9A (0.52) | MAPTTRPV1POLBNPC1ATM | |
| SCHEMBL11663687 | 0.82 | RAB9A (0.48) | MAPTTRPV1POLBNPC1KMT2A | |
| SCHEMBL10105952 | 0.80 | NPC1 (0.57) | MAPTTRPV1POLBNPC1CASP3 | |
| SCHEMBL11775723 | 0.80 | KDM4E (0.60) | MAPTPOLBNPC1CASP3ATM | |
| SCHEMBL11773236 | 0.80 | KDM4E (0.66) | MAPTPOLBNPC1CASP3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939194-A | Bis-2-azomethine pigments, process for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |