SCHEMBL10106017

SCHEMBL10106017

C(=C/c1ccc(N(c2ccccc2)c2ccc(OCOc3ccc(N(c4ccccc4)c4ccc(/C=C/c5ccccc5)cc4)cc3)cc2)cc1)\c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.61
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
MTOR P42345 2/20 0.53
THPO P40225 1/20 0.53
HIF1A Q16665 1/20 0.53
RAB9A P51151 1/20 0.53
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 2/20 0.51
GMNN O75496 2/20 0.51
LMNA P02545 2/20 0.51
PMP22 Q01453 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
BLM P54132 1/20 0.51
CHRNA7 P36544 8/20 0.50
TP53 P04637 2/20 0.50
CYP2D6 P10635 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13930225 0.90 RELA (0.50) RELACYP1A2CYP3A4MTORTHPO
SCHEMBL8896821 0.87 ALDH1A1 (0.48) RELACYP1A2CYP3A4HIF1AKDM4E
SCHEMBL10866111 0.86 RELA (0.77) RELACYP1A2CYP3A4MTORTHPO
SCHEMBL11033784 0.86 RELA (0.77) RELACYP1A2CYP3A4MTORTHPO
SCHEMBL13720595 0.83 RELA (0.64) RELACYP1A2CYP3A4KDM4EALDH1A1
SCHEMBL10128952 0.83 RELA (0.64) RELACYP1A2CYP3A4KDM4EALDH1A1
SCHEMBL243731 0.83 RELA (0.64) RELACYP1A2CYP3A4KDM4EALDH1A1
SCHEMBL243730 0.83 RELA (0.64) RELACYP1A2CYP3A4KDM4EALDH1A1
SCHEMBL13720653 0.83 RELA (0.64) RELACYP1A2CYP3A4KDM4EALDH1A1
SCHEMBL133152 0.83 RELA (0.64) RELACYP1A2CYP3A4KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8974998-B2 Method of image forming with a photoreceptor and toner MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-10 US disclosed
US-8974998-B2 Method of image forming with a photoreceptor and toner MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-10 US disclosed
US-8871413-B2 Toners for electrostatic-image development, cartridge employing toner for electrostatic-image development, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-28 US disclosed
US-8871413-B2 Toners for electrostatic-image development, cartridge employing toner for electrostatic-image development, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-28 US disclosed
US-8741530-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-06-03 US disclosed
US-8741530-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-06-03 US disclosed
US-20130143156-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-06-06 US disclosed
US-20130143156-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-06-06 US disclosed
US-20130059250-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-07 US disclosed
US-20130059250-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-07 US disclosed
US-20110038650-A1 TONERS FOR ELECTROSTATIC-IMAGE DEVELOPMENT, CARTRIDGE EMPLOYING TONER FOR ELECTROSTATIC-IMAGE DEVELOPMENT, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2011-02-17 US disclosed
US-20110038650-A1 TONERS FOR ELECTROSTATIC-IMAGE DEVELOPMENT, CARTRIDGE EMPLOYING TONER FOR ELECTROSTATIC-IMAGE DEVELOPMENT, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2011-02-17 US disclosed
US-20100316411-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20100316411-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20100316412-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20100316412-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20090180807-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-07-16 US disclosed
US-20090180807-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-07-16 US disclosed
US-20090041500-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-12 US disclosed
US-20090041500-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-12 US disclosed