Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102080 | 0.88 | NR1H4 (0.37) | NR1H4GRIN2BLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL10106911 | 0.81 | PDE4D (0.45) | PDE4DRECQLLMNAPPARGPPARA | |
| SCHEMBL10106913 | 0.80 | GRIN2B (0.44) | GRIN2BPPARGPPARA | |
| SCHEMBL10107287 | 0.78 | MAOB (0.43) | PDE4DRECQLLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL10106925 | 0.76 | SMN1; SMN2 (0.49) | PDE4DRECQLLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL10106852 | 0.76 | PTPN7 (0.46) | PDE4DRECQLLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL10107036 | 0.74 | RECQL (0.43) | PDE4DRECQLLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL15255539 | 0.74 | NPC1 (0.48) | RECQLLMNASMN1; SMN2PPARGPPARA | |
| SCHEMBL10107226 | 0.72 | MAOA (0.42) | PDE4DRECQLLMNAPPARGPPARA | |
| SCHEMBL10106910 | 0.72 | NPC1 (0.46) | RECQLPPARGPPARAPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | THE UNIVERSITY OF MELBOURNE of ROYAL PARADE PARKVILLE (AU) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | PTGES2, PTGES, PTGES3 | NR1H4 27/4885PDE4D 1364/4885GRIN2B 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.