SCHEMBL1010764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1011608	0.86	ACACB (0.46)	PDE10AHDAC1ATMOGASMN1; SMN2
	SCHEMBL2427846	0.86	P2RY12 (0.62)	HRH3P2RY12ATMOGAHPGD
	SCHEMBL31368898	0.84	P2RY12 (0.50)	HRH3P2RY12ATMOGAHPGD
	SCHEMBL8085019	0.84	P2RY12 (0.50)	HRH3P2RY12ATMOGAHPGD
	SCHEMBL30964849	0.82	TP53 (0.42)	PDE10AHPGDSMN1; SMN2GPR119MAPT
	SCHEMBL5216155	0.82	HRH3 (0.64)	HRH3P2RY12HPGDSMN1; SMN2GPR119
	SCHEMBL12723527	0.81	HRH3 (0.53)	HRH3P2RY12PDE10AOGAUSP30
	SCHEMBL22795888	0.80	PDE10A (0.50)	PDE10AHDAC1GPR119USP30CRBN
	SCHEMBL928501	0.80	PDE10A (0.50)	PDE10AHDAC1GPR119USP30CRBN
	SCHEMBL31274442	0.80	PDE10A (0.50)	PDE10AHDAC1GPR119USP30CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.