SCHEMBL1011608

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1010764	0.86	HRH3 (0.50)	GPR119ATMNPSR1MAPTLMNA
	SCHEMBL12480371	0.85	GPR119 (0.56)	GPR119ATMMAPTOGA
	SCHEMBL31270870	0.83	GPR119 (0.56)	ACACBGPR119NPSR1MAPTMEN1
	SCHEMBL31271007	0.83	GPR119 (0.56)	ACACBGPR119ATMNPSR1MAPT
	SCHEMBL2064933	0.81	DPP4 (0.45)	GPR119NR1H2ATMNPSR1MEN1
	SCHEMBL2064934	0.81	DPP4 (0.45)	GPR119NR1H2ATMNPSR1MEN1
	SCHEMBL22720768	0.81	GPR119 (0.50)	ACACBGPR119NR1H2MAPTPDE10A
	SCHEMBL12723192	0.80	CYP3A4 (0.48)	ACACBGPR119ATMNPSR1MAPT
	SCHEMBL12341266	0.80	GPR119 (0.51)	GPR119ATMNPSR1MAPTMEN1
	SCHEMBL1012386	0.80	ACACB (0.48)	ACACBNPSR1MAPTPDE10AOGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.