Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 5/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2427846 | 0.87 | P2RY12 (0.62) | P2RY12HRH3ATMCRBNRET | |
| SCHEMBL8085019 | 0.85 | P2RY12 (0.50) | P2RY12HRH3ATMCRBNRET | |
| SCHEMBL1010764 | 0.84 | HRH3 (0.50) | P2RY12HRH3ATMCRBNGPR119 | |
| SCHEMBL16846258 | 0.81 | P2RY12 (0.52) | P2RY12HRH3CRBNOGASMN1; SMN2 | |
| SCHEMBL5216155 | 0.81 | HRH3 (0.64) | P2RY12HRH3GPR119SMN1; SMN2HPGD | |
| SCHEMBL27413018 | 0.80 | MEN1 (0.44) | ATMRETGPR119SMN1; SMN2NPSR1 | |
| SCHEMBL1640736 | 0.80 | CRBN (0.54) | HRH3CRBNRETHPGDALDH1A1 | |
| SCHEMBL32679621 | 0.80 | ACACB (0.46) | ATMGPR119OGANPSR1MAPT | |
| SCHEMBL20046086 | 0.80 | GPR119 (0.48) | P2RY12CRBNRETGPR119MAPT | |
| SCHEMBL23538928 | 0.79 | RET (0.49) | CRBNRETGPR119EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119384420-A | Novel PAR-2 inhibitors | 多曼治疗学公司 | 2025-01-28 | — | — | CN | disclosed |