SCHEMBL10108451

SCHEMBL10108451

c1ccc(-c2ccc(N(c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)c3cccc4c3sc3c4ccc4c3c3ccccc3n4-c3ccccc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSPO P30536 2/20 0.35
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10108493 0.99 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL10108453 0.95 L3MBTL1 (0.38) KDM4EATML3MBTL1
SCHEMBL24825413 0.89 CYP1A1 (0.37) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL12283480 0.88 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL12283832 0.88 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL12283105 0.88 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL14755957 0.87 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL14755984 0.87 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17426356 0.86 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL17194480 0.86 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9246107-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-01-26 US disclosed
US-9246107-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-01-26 US disclosed
EP-2450975-B1 Compound for organic optoelectronic device and organic light emitting diode including the same CHEIL IND INC (KR) 2014-01-08 EP disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 US disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE AOX1, OCIAD1, OCIAD2 KDM4E 2197/4885ATM 3878/4885L3MBTL1 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.